The DEO has implemented a mixed system to provide access to a broad spectrum of technological services. The DEO Technological Units are conceived as high-tech structures run by specialized technologists in coordination with DEO scientists in order to guarantee a constant technological update and flexibility to the needs of the groups. Standard services are provided by Cogentech (Consortium for Genomic Technologies, owned by IEO and IFOM), whose facilities are commercial and open to external users.

The Technological Units of the DEO include the Genomic Unit, the Crystallography Unit and the Mass Spectrometry Unit.

Cogentech includes facilities for mouse work, protein and antibody production and DNA analyses (Core Support Units).