Research overview. IEO is founding member of the two most important international scientific consortia dedicated to the use of Next Generation Sequencing technologies to investigate modifications of DNA and its associated proteins in normal and pathological tissues, Blueprint (www.blueprint-epigenome.eu) and IHEC (International Human Epigenome Consortium, ihec-epigenomes.org).

IEO considers research in genomics a strategic priority for the next decade. Since 2009 IEO has made significant investments in Genomics in collaboration with the Center for Genomic Sciences of the Italian Institute of Technology (IIT) hosted at our Campus. Currently, about ten research groups of the DEO-IEO and additional groups at the IIT are actively using Next Generation Sequencing technologies to investigate genome regulation and structure in the context of different aspects of tumor biology. This has led to the development of a highly integrated genomic research community including more than one hundred wet biologists, about 30 computational scientists, and a Technological Unit dedicated to genomic platforms and run in partnership by IEO and IIT.

The genomic research carried out at IEO has already led to a number of high-impact scientific publications and patents.