The collaboration between all the components of the Department lead to the optimization of the process of diagnosis and cure of patients. While a multidisciplinary approach to the diseases is mandatory nowadays, all departments participate at several scheduled meetings. The combination of metabolic and functional imaging offers the possibility of a more accurate diagnosis and therapy because imaging represents the optimal way to stage, treat and follow patients. Teams of specialists are in fact dedicated to each tumor site and in such a manner, through the collegial evaluation of images and clinical informations and evaluating different approaches, will be possible the best choice in each particular clinical situation. Also the process of enrolling patients to the different therapeutical strategies, once decided, will be easier and faster and each treatment will be personalized.