Neuroendocrine tumors (NETs) of the gastroenteropancreatic (GEP) tract are rare malignancies with a heterogeneous clinical behavior. For low grade resectable tumors radical surgery represents the best bet. However it is debated if the single small pancreatic nodule, often incidentally detected, should be always resected or followed-up.
Intermediate grade locally advanced radically resected panNETs have a concrete risk of relapse. Therefore neoadjuvant or adjuvant therapies could have a role in this context, but they have not been investigated so far.
Finally surgery can have a role also in the context of a metastatic disease, mainly for primary tumor removal. Due to these features and lack of absolute evidence GEP NET patients should be managed within multidisciplinary dedicated teams of referral centers. This workshop is focused on the interaction between clinicians and surgeons from NET referral centers in three different clinical settings: localised radically resected panNET, locally advanced resectable or potentially resectable panNET, and metastatic GEP NET.
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